Frederick Muhlenberg was the great-great grandson of Major General John Peter Gabriel Muhlenberg, whose statue is in the Rotunda of the Capital, Washington, D. C. John Peter Gabriel Muhlenberg’s brother was Frederick Augustus Conrad Muhlenberg, Speaker of the first and third House of Representatives, and the first signer of the Bill of Rights. He was elected as a Republican to the Eightieth Congress (January 3, 1947-January 3, 1949) and was an unsuccessful candidate for reelection in 1948 to the Eighty-first Congress.